Category: Seroxat Link 10 : Paroxetine Womb

Seroxat Link 10 : Paroxetine Womb : Foetus Poisoning


GSK admit that Seroxat can double the risk of heart defects and other malformations in babies born to Mothers ingesting Seroxat during pregnancy. This has been well documented already and the FDA and MHRA have issued warnings recently about the risks to newborns and the unborn.
There is also much documentation and research about babies suffering withdrawal and other side effects from exposure to Seroxat. But this is still a relatively new issue and there hasn’t been a lot of coverage of these terrible tragedies or these issues in the mainstream media ( although there is a lot of info on the internet about it).. It is a sensitive issue, but I feel it is one that needs to be explored further…

Seroxat was also recently reclassified from a category C drug to a category D…
Which means it does “officially” pose a significant risk to the foetus…

But… In this post I am going to concentrate on some other interesting information relating to Seroxat in the womb , and what I am interested in also is; how do we relate the malformations in newborns to the affects on adult use of Seroxat?

Well, you will notice that from a Seroxat study from the EMC website , there is an interesting fact about Seroxat’s effects on pups (baby rats)…
There was increased pup mortality ( dead baby rats) and also delayed ossification (delayed development/fusion of bones) was observed in the pups..
You can see from the links that problems with Ossification has actually happened to babies born with Seroxat induced defects …

When the seams of the skull close prematurely ( they fail to fuse or ossify) it is called craniosynotosis

Could this development of craniosytosis possibly be related to the severe headaches and head pressure documented in Seroxat withdrawal cases in adults?

What is craniosynotosis?

Craniosynostosis is the term for a group of conditions in which a baby’s head develops abnormally because the seams between the bones close prematurely. This prevents the head from developing normally and may be associated with changes in the upper facial bones. Craniosynostosis can usually be recognized at birth, but for a very small number of children it does not become obvious until one year of age or older.

Why was this not noted and explored further? and why did GSK not draw attention to this? Why was this dismissed?

Reproduction toxicity studies in rats have shown that paroxetine affects male and female fertility. In rats, increased pup mortality and delayed ossification were observed. The latter effects were likely related to maternal toxicity and are not considered a direct effect on the foetus/neonate. So , how does this relate to adults? …

Well, considering the drugs affects on the foetus can be seen as an indication that Seroxat can damage the Skull, the internal organs and cause breathing problems in neonates…. surely similar effects could happen in adult use of Seroxat?

Another example of how we can relate the problems seroxat causes in babies , is the evidence of babies born with PPHN (Persistent pulmonary hypertension) from exposure to Seroxat in the womb. PPHN is a life-threatening condition that typically involves severe respiratory failure in a newborn infant and requires immediate treatment.

Would this explain the breathing problems which have been reported extensively by adults suffering Seroxat withdrawal affects?…

There has also been widespread reporting of Seroxat affecting male fertility…

This was also reported in rats ..

    (See Links At Bottom Of Post)

Fertility

Animal studies in rats found impaired pregnancy rates at high concentrations. High doses over many weeks led to irreversible atrophic changes in the seminiferous tubules of male rats.

Why has more attention not been brought to Paroxetine’s effects on rats, babies, in the womb and its relation to how it affects adults… ?

http://www.medscape.com/viewarticle/450390_7

http://emc.medicines.org.uk/emc/industry/default.asp?page=displaydoc.asp&documentid=2057

http://seroxatkillsbabies.wordpress.com/

( Blog from mother who gave birth to a baby with a paxil induced heart defect)