Category: Neal Ryan

Seroxat/Paxil Study 329: Nobody Pinned Anything on Us


http://brodyhooked.blogspot.ie/2012/07/inside-paxil-study-329-courtesy-justice.htmlhttp://brodyhooked.blogspot.ie/2012/07/inside-paxil-study-329-courtesy-justice.html

“…Inside Paxil Study 329, Courtesy the Justice Department

I’ve previously discussed the now-infamous Study 329, which took discouraging data on the efficacy and safety of paroxetine (Paxil) in kids and spun it into an article claiming excellent results:
http://brodyhooked.blogspot.com/2011/11/will-brown-university-investigate.html

Thanks to the U.S. Justice Dept. complaint in the suit recently settled by GlaxoSmithKline for a record $3B: http://www.justice.gov/opa/documents/gsk/us-complaint.pdf
–we can follow the history of this study in more detail, based on the internal GSK documents discovered during the proceedings, and see just how the data were manipulated for marketing purposes.

Study 329, directed by Dr. Martin Keller of Brown University, was one of 3 clinical studies in children and adolescents that were all interpreted by GSK scientists between August and October, 1998 to be discouraging. Study 329’s protocol specified two primary endpoints, and on neither measure did Paxil do better than placebo. The study also logged in 11 serious adverse reactions to Paxil, much more than in the placebo group, including 5 with agitated or suicidal behavior, the major risk for which eventually the FDA issued a black-box warning for the SSRI class of antidepressants…”

 

http://davidhealy.org/study-329-response-from-the-authors/#comment-44667

 

What exactly did Martin Keller mean when he said that ‘nobody ever pinned anything on us’? (in regards to his involvement in the Paroxetine-Paxil/Seroxat Study 329).

Interesting ‘choice of words’ methinks…

 


 

Study 329: Nobody Pinned Anything on Us

March, 31, 2016 | 2 Comments

 

 

Seroxat Trebles The Risk Of Suicide For Under 18’s


 

What’s the difference for over 18’s? Over 21’s? Under 25’s? Adults?How suicidal does it make those age-groups?

What is GSK still hiding from the public all these years later?

Maybe in 2014 we’ll find out?