“…The findings, published in the online journal Public Library of Science Medicine, showed that, overall, taking SSRIs increased the likelihood of a violent conviction by 19%….
… If our findings related to young people are validated in other designs, samples and settings, warnings about an increased risk of violent behaviours while being treated with SSRIs may be needed…”
“It may be that one of the disclosures that doctors need to make warning of irritability, hostility and violent crime,” he said. “You need to watch out. And If you do feel increased hostility, aggression, violent thoughts you should go back to your GP and talk about that.”
Antidepressants dramatically raise the risk of young people committing violent crimes, shock research suggests.
Selective serotonin reuptake inhibitors (SSRIs) – which include drugs like Prozac – are a common type of antidepressant.
They are prescribed to millions of Brits every year.
SSRIs are usually the first choice medication for depression because they generally have fewer side effects than most other types of antidepressant.
But a new study shows that taking SSRIs raise the likelihood of someone aged 15 to 24 being convicted for an act of violence by 43%.
Young people taking antidepressants such as Prozac and Seroxat are significantly more likely to commit violent crimes when they are on the medication, but taking higher doses of the drugs appears to reduce that risk, scientists said on Tuesday.
In research published in the PLoS Medicine journal, the scientists said that while their finding of a link does not prove that such drugs cause people to be more violent, further studies should be conducted and extra warnings may be needed in future when they are prescribed to people aged 15 to 24.
Selective Serotonin Re-uptake Inhibitors (SSRIs) are a class of widely prescribed drugs, including fluoxetine, branded by Eli Lilly as Prozac, and GlaxoSmithKline’s paroxetine, branded as Paxil or Seroxat, designed to ease symptoms of anxiety and depression.
For this work, researchers led by Seena Fazel of Britain’s Oxford University used a unique study design which aimed to avoid confounding factors by comparing the same individuals’ behavior while they were on and while they were off medication.
“The point of the design is that we’re comparing people with themselves,” Fazel told reporters at a briefing, adding that this helped minimize the impact of genetics or lifestyle factors.
Using matched data from Sweden’s prescribed drug register and its national crime register over a three-year period, they found about 850,000 people were prescribed SSRIs, and 1.0 percent of these were convicted of a violent crime.
While in most age groups the likelihood of criminal violence was not significantly different when people were taking SSRIs and when they were not, in 15-24 year-olds there was a distinct increase – of 43 percent – in their risk of committing violent crime while on the medication.
The results also found a higher risk of young people being involved in violent arrests, non-violent convictions and arrests, non-fatal injuries and having alcohol problems when they were taking the antidepressants – but also that those who took lower doses had a higher risk of being violent.
Fazel stressed that the findings raised several questions and should be investigated further before any changes were recommended on prescribing SSRIs. He said it was possible that young people taking lower doses of antidepressants were not being “fully treated” for their mental disorder, leaving them more likely to engage in impulsive behavior.
He added, however, that if the results are confirmed in further studies, “warnings about the increased risk of violent behavior among young people taking SSRIs might be needed”.
Una Butler, whose husband killed their two children, calls for a change in mental health legislation
Tuesday 8th October 2013
Una Butler, whose husband tragically murdered their two daughters and himself in November 2010, spoke to Mark Cagney and Sinead Desmond on TV3’s Ireland AM this morning.
“The medical profession might have treated John differently having heard my side of the story, and that would be without discussing what John was telling them, you know, without discussing it with me, so they’d have a greater insight into his behaviours at home because I don’t believe that he’d have told them everything about his behaviours at home”
“I believe that if I was educated on the illness, if there was a support liaison person there for the family to explain the illness maybe the side-effects of the medication, the effects that it would have had on John, that I would have been able to understand it better.”
Postpartum Depression: Mother Murders Baby & Self
Paragraph one reads: “Nollaig had been diagnosed with post-natal depression but the medication she was prescribed did not seem to be very effective.”
When the single dad-of-one complained to Black about her neglect of the dog, the pair argued and Black fatally stabbed Malone.
Black phoned the emergency services and admitted to gardai she had inflicted the fatal wound but said she hadn’t intended to kill him.
Before passing sentence, Mr Justice Paul Carney said the crime was at the top end of the scale as the killer had equipped herself with a knife before the attack.
The court heard Black been drinking alcohol and taking anti-depressants on the day of the attack.