Seroxat For Sale : GSK Makes £435 Million A Year From Seroxat Sales


http://www.thepharmaletter.com/file/110876/glaxosmithkline-4th-qtr-returns-to-profit-but-below-expectations.html

Amazing,

Seroxat (Paxil/Aropax) is one of the most controversial drugs of the past 20 years:

Birth defects, severe withdrawal symptoms, suicide, self harm, addiction, dependence, extreme debilitating side effects, controversy, lawsuits, headlines, fraud, corrupt sales practices, corrupt doctors and psychiatrists, documentaries, you tube videos, blogs, books, websites, users groups, internet forums….

Seroxat has it all…

Yet, GSK still makes £435 million a year on sales of this nasty drug.

You would have to ask? Are those whom remain on Seroxat too addicted to come off it…
Is this profiting from addiction?..

Most likely..

GSK’s cardiovascular and urogenital franchise generated 2011 turnover of £2.47 billion, a year-on-year rise of 8%. Within this, benign prostatic hyperplasia drug Avodart (dutasteride) sales reached £748 million, a leap of 20%, but blood thinner Arixtra (fondaparinux) declined 7% to £276 million. The central nervous system franchise was down 2% to £1.72 billion for the year, With Keppra (levetiracetam) contributing £53 million, up 20%, and Lamictal (lamotrigine) for seizures and bipolar disorder adding 536 million, a rise of 8%, while the antidepressant Seroxat/Paxil (paroxetine) generated £435 million sales, a fall of 13%. Oncology and emesis product contributed £693 million sales, up 2%, with breast cancer drug Tyverb/Tykerb (lapatinib) rising by the same percentage to £231 million.

Advertisements

9 comments

  1. Nick

    Its not the worst and in fact only a small number of people have been badly effected by Paroxetine. It helps more people than it harms which is why it’s still being given out. The only problem was original marketing of the medication for children and also the idiotic strapline that it is not addictive when in some ways all SSRI’s are addictive and all require tapering off methods to stop them safely.

    The worst medications in the past 20 years would have to be Merck’s Vioxx,Propecia and Fosamax. Two of these have been scrapped because of the amount of harm they can cause. Propecia that causes permanent side effects that Boots,Lloyds and NHS still keep recommending as a hair loss medication is ruining many mens lives. The side effects are permanent in 95% of users and ALL users experience side effects not just 2% as claimed.

    Seroxat has been very helpful for me and have never had any side effects nor had any suicidal thoughts.

    What GSK did was not only bad for younger vulnerable people but has totally damaged the reputation of Paroxetine. It is very good for many people and is very effective, however after all the controversies and the lies, not many people will want to take Paroxetine and instead will rely on useless treatments such as Citalopram or the strange behaviour causing pills known as Sertraline.

    Hopefully, the bad marketing practices and corruption will not be as rife, the company needs a shake up and overhaul of its operations, GSK is very good at producing and researching new treatments, I understand it is a business and a profit is to be made but really they have to go about things with more care and have some sort of ethical practice. I think the company should be split into different sectors and de-merged and become seperate companies as well as bringing in new people outside of GSK to manage the operations. I just don’t see any other way.

    • truthman30

      With all due respect Nick… You don’t speak for the many who have been damaged by Seroxat- and if you think it has benefited you that’s great , however I would say your opinion would be quite different if you tried to come off it cold turkey after a few years… how long are you on it?

  2. Nick

    Your not meant to come off any SSRI cold turkey. I was on sertraline for 8 months and wad literally bed bound when I went three days without it.

    Regardless of how long you take SSRI’s you must not stop them cold turkey. Its very dangerous! Any good prescribed should be informing patients about this, its the basics.

    I have been using Paroxetine for about 6 yeara I’ve used citalopram,mirtazipine and sertraline which were awful.

    If SSRI’s could be stopped overnight they would be available without prescription! But because the brain starts missing the level of serotonin, the body goes into chaos, I do agree that Paroxetine takes longer to quit gradually but that’s not much different to other SSRi’s.

    But I must stress that nobody should quit any SSRI’s,SNRI’s or anti psychotics cold turkey! It should be done gradually and managed by a GP.

    Doctors who recommend cold turkey are irresponsible. I’ve heard stories how diazepam I being prescribed for months on end! Why! Its only meant to be for a few days as its addictive, again totally irresponsible practice.

  3. truthman30

    Well Nick, until you try to come off Seroxat, then you won’t know how bad it is. Many people were not warned of Seroxat side effects such as violence, akathisia, withdrawal etc, that’s the issue. The drug company down played side effects and people suffered, some died because they weren’t warned. Doctors are still ill informed and ignorant too and many people would like to come off Seroxat/Paxil but they cannot- is that fair? I don’t think so.

    • Nick

      Ive been on and off it for some time and used other SSRI’s. The very exact things you mention about Seroxat I experienced with Sertraline (Lustral). Citalopram was very easy to get off but the side effects I had when using was bad.

      When stopping Paroxetine in the past I reduce the dose by 10mg every 2 months, so when I was on 30mg the previous time, I reduced it to 20mg and then after another 2 months I reduced it to 10mg by breaking the 20mg tablets in half, after a fortnight, I reduced it again by taking 10mg every 72 hours. Then after a further fortnight withdrew completely, the effect after this was feeling very tired and sense of not being bothered to do anything for a few days and that disappeared and was back to my usual self.

      So you see, I do agree it is slightly harder to get off but so is Sertraline.

      Just to note, I stopped Sertraline cold turkey by switching to Paroxetine and had no withdrawal effect, so this could be another way off Seroxat, to take another SSRI for a short while.

      • truthman30

        Well, we all have varying experiences on these drugs but in my years of research it is apparent to me that Paroxetine is particularly nasty…

  4. Nick

    IMPORTANT NOTICE: To anyone reading, this is NOT official advice on withdrawing from a SSRI and is not intended to advise any SSRI user to withdraw using an Anti-Histimine product. If you have issues or questions or are thinking of withdrawing your SSRI, please contact your GP/prescriber for accurate and professional advice. If you have experienced a severe reaction to any kind of medication, you should contact your nearest A&E department and report your problem to the MHRA using the yellow card system.

    Hi there,

    Just thought I’d update you on recent events.

    I decided to come off Seroxat as I feel I no longer need it, I feel very good now.

    I decided to do it cold turkey, yes it is very risky but I just couldn’t be bothered to go on the tapering off process and to go to the doctors. Well anyway it has been 8 days now and I have very little withdrawal effects.

    The first few days weren’t so good and I experienced that electric shock feeling with every movement, this is common with all SSRI’s when quitting cold turkey. I suffer from hayfever and took a large dose of Chlorphenamine(piriton), guess what, all the withdrawal effects disappeared!

    Can you explain how Chlorphenamine can decrease the withdrawal effects of an SSRI? or any theories, So I have been using Chlorphenamine for the past 8 days, two 4mg tablets in the morning and two 4mg tablets in the evening/late afternoon.

    This is day 8 now and all the withdrawal effects have almost disappeared, today I only took one 4mg tablet in the morning as my hayfever is not that bad.

    Is this just coincidence or is there some relation between Chlorphenamine and Paroxetine?

    IMPORTANT NOTICE: To anyone reading, this is NOT official advice on withdrawing from a SSRI and is not intended to advise any SSRI user to withdraw using an Anti-Histimine product. If you have issues or questions or are thinking of withdrawing your SSRI, please contact your GP/prescriber for accurate and professional advice. If you have experienced a severe reaction to any kind of medication, you should contact your nearest A&E department and report your problem to the MHRA using the yellow card system.

      • Nick

        This is an extract from:
        http://survivingantidepressants.org/index.php?/topic/1454-dr-david-healy-on-prolonged-antidepressant-withdrawal-syndrome-2009/

        Treating Severe Discontinuation Difficulties
        In terms of the initial treatment of severe discontinuation difficulties, there are serotonergic and non-serotonergic options.

        The serotonergic options as outlined in a number of withdrawal protocols involve going on a serotonin reuptake inhibitor such as fluoxetine or imipramine, often in liquid form and tapering extremely gradually.

        A second option involves moving to a tricyclic antidepressant or an antihistamine or St John’s Wort on the basis that these share antihistaminic and serotonin reuptake inhibiting properties in common but are less potent (“gentler”) than SSRIs.

        A third option involves treating with agents acting on different systems. Apparent success has been reported with choline-esterase inhibitors or lamotrigine. These have appeared in some instances to ease withdrawal problems in individuals who have found it very difficult to get off treatment.
        (Ends Here)

        So it looks like someone has beaten me to it, it mentions the use of antihistamines.

        My findings show that the Antihistamine Chlorphenamine works best, Diphenhydramine should be avoided.

        For those with severe withdrawal symptoms, I really don’t know why this method has not been promoted or publicized. Both Seroxat and Piriton are trademarks of GSK. So i’m sure this will work in there favour and actually improve the image of Paroxetine. Despite the previous mistakes GSK made with Paroxetine, it still remains a very helpful and tolerant medicine for millions,

        Why on earth wasn’t this studied before!

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s